FOXM1 Antikörper (AA 713-763)

Produktnummer ABIN7449736

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FOXM1 in WB und IP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für FOXM1 Antikörper (AA 713-763) (ABIN7449736)

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-FOXM1 Antikörper

Bindungsspezifität: AA 713-763

Verwendungszweck: Rabbit anti-FOXM1 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 713 and 763

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu FOXM1

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Andere Bezeichnung: FOXM1

Hintergrund: Background: FOXM1 belongs to a large family of Forkhead transcription factors that possesses a winged-helix DNA-binding domain called Forkhead box (FOX). It is a transcription factor critical to cell cycle progression via its role in coordinating the G2/M phase transition. FOXM1 is ubiquitously expressed in proliferating cells but is absent in differentiated cells. FOXM1 overexpression has been detected in a variety of tumor types including breast, lung, prostate, and liver cancer, and appears to be involved in tumorigenesis-associated processes such as angiogenesis and metastasis. In light of these findings, FOXM1 has recently become an attractive target for anti-cancer therapy.

Gen-ID: 2305

NCBI Accession: NP_973731

UniProt: Q08050

Pathways: Positive Regulation of Response to DNA Damage Stimulus