Rekombinanter IDO1 Antikörper (AA 1-403)
Kurzübersicht für Rekombinanter IDO1 Antikörper (AA 1-403) (ABIN7449662)
Target
Alle IDO1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-403
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Verwendungszweck
- Rabbit anti-IDO1 Recombinant Monoclonal Antibody [BLR040F]
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Immunogen
- residues 1-403 (full length)
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Isotyp
- IgG
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Applikationshinweise
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IP: 15 µL/1 mg lysate
WB: 17:40:00
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 400 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
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Andere Bezeichnung
- IDO1
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Hintergrund
- Background: Indoleamine 2,3-dioxygenase (IDO1) is a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. IDO1 acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. It is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan [taken from NCBI Entrez Gene (Gene ID: 3620)].
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Gen-ID
- 3620
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NCBI Accession
- NP_002155
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UniProt
- P14902
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Pathways
- Activated T Cell Proliferation
Target
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