Merlin Antikörper (C-Term)
Kurzübersicht für Merlin Antikörper (C-Term) (ABIN7449601)
Target
Alle Merlin (NF2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Rabbit anti-NF2 Antibody, Affinity Purified
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Homologie
- Rat
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 550 and C-term
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Isotyp
- IgG
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Applikationshinweise
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IP: 1 - 4 μg/mg lysate
WB: 1:5,000 - 1:15,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Merlin (NF2) (Neurofibromin 2 (NF2))
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Andere Bezeichnung
- NF2
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Hintergrund
- Background: Mutations in NF2 (neurofibromin 2) are associated with neurofibromatosis type II which is characterized by Schwann cell tumors (schwannomas) which are benign slow-growing tumors that are resistant to chemotherapeutic intervention. NF2 is a membrane/cytoskeletal associated protein that has been classified as a novel type of tumor suppressor due to its function in membrane organization versus a classic tumor suppressor function that regulates cell cycle machinery.
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Gen-ID
- 4771
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NCBI Accession
- NP_057502
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UniProt
- P35240
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Pathways
- Cell-Cell Junction Organization
Target
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