MTA2 Antikörper (AA 500-550)
Kurzübersicht für MTA2 Antikörper (AA 500-550) (ABIN7449600)
Target
Alle MTA2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 500-550
-
Verwendungszweck
- Rabbit anti-MTA2 Antibody, Affinity Purified
-
Homologie
- Mouse
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 500 and 550
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IP: 1 - 4 μg/mg lysate
WB: 1:5,000 - 1:15,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
-
Andere Bezeichnung
- MTA2
-
Hintergrund
- Background: MTA2 (metastasis-associated protein 2) is a component of the NuRD (nucleosome remodeling and histone deacetylation) complex. MTA2 is highly similar to MTA1 and was identified as a factor differentially expressed in a carcinoma cell line. MTA2 can repress p53-dependent transcriptional activation by enhancing its deacetylation. MTA1 has also been shown to function as a corepressor for ligand-induced estrogen receptor (ER) transactivation. As part of the NuRD complex MTA2 represses ERalpha transactivation activity by modulating the acetylation status of ERalpha.
-
Gen-ID
- 9219
-
NCBI Accession
- NP_004730
-
UniProt
- O94776
-
Pathways
- Chromatin Binding
Target
-