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Rekombinanter CD8 alpha Antikörper (AA 185-235)

CD8A Reaktivität: Human FACS, IHC, WB, IF (p), mIF Wirt: Kaninchen Monoclonal BLR044F unconjugated Recombinant Antibody

Produktnummer ABIN7449561

Datenblatt (PDF)

Target Alle CD8 alpha (CD8A) Antikörper anzeigen

CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Antikörpertyp

Recombinant Antibody
Bindungsspezifität
16

15

10

9

9

9

8

7

6

6

5

5

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 185-235
Reaktivität
184

115

46

37

11

7

3

2

2

2

2

2

2

2

2

1

1
Human
Wirt
148

121

99
Kaninchen
Passende Sekundärantikörper
Klonalität
266

98

1
Monoklonal
Konjugat
117

41

30

28

26

9

8

8

8

7

6

5

5

5

5

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD8 alpha Antikörper ist unkonjugiert
Applikation
277

107

95

68

59

46

23

19

15

14

14

11

10

8

8

7

7

6

5

3

3

3

2

2

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Multiplex Immunofluorescence (mIF)

Verwendungszweck

Rabbit anti-CD8 alpha Recombinant Monoclonal Antibody [BLR044F]

Immunogen

between AA 185 and 235 (C-term)

Klon

BLR044F

Isotyp

IgG

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Applikationshinweise

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
WB: 17:40:00

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

250 μg/mL

Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Haltbarkeit

12 months
Target

CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Andere Bezeichnung

CD8 alpha (CD8A Produkte)

Synonyme

cd8 antikoerper, LOC100136450 antikoerper, BB154331 antikoerper, Ly-2 antikoerper, Ly-35 antikoerper, Ly-B antikoerper, Lyt-2 antikoerper, zgc:136643 antikoerper, CD8 antikoerper, Leu2 antikoerper, MAL antikoerper, p32 antikoerper, RHACD8-4 antikoerper, CD8a molecule antikoerper, uncharacterized LOC100125537 antikoerper, CD8 alpha antikoerper, CD8 antigen, alpha chain antikoerper, T-cell surface glycoprotein CD8 alpha chain antikoerper, Cd8a antikoerper, LOC100125537 antikoerper, LOC100136450 antikoerper, CD8A antikoerper, cd8a antikoerper, LOC100126556 antikoerper

Hintergrund

Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain [taken from NCBI Entrez Gene (Gene ID: 925)].

Gen-ID

925

NCBI Accession

NP_001759

UniProt

P01732

Pathways

T-Zell Rezeptor Signalweg