CD45RO Antikörper
Kurzübersicht für CD45RO Antikörper (ABIN7449553)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Mouse anti-CD45RO Monoclonal Antibody, Purified [UCHL-1]
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Immunogen
- Cultured T-cells from an IL-2-dependent T-cell line (CA1)
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Isotyp
- IgG
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anti-CD45RO (CD45RO) antibody
CD45RO Reaktivität: Human, Maus, Ratte IHC (p), WB, IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD45RO (CD45RO) antibody (PE)CD45RO Reaktivität: Rind (Kuh), Ziege FACS Wirt: Maus Monoclonal IL-A116 PE
anti-CD45RO (CD45RO) antibodyGMP Grade CD45RO Reaktivität: Human FACS, IHC, IP Wirt: Maus Monoclonal UCHL1 unconjugated
anti-CD45RO (CD45RO) antibody (FITC)GMP Grade CD45RO Reaktivität: Human FACS Wirt: Maus Monoclonal UCHL1 FITC
anti-CD45RO (CD45RO) antibody (mFluor™450)GMP Grade CD45RO Reaktivität: Human FACS Wirt: Maus Monoclonal UCHL1 mFluor™450
anti-CD45RO (CD45RO) antibody (APC)GMP Grade CD45RO Reaktivität: Human FACS Wirt: Maus Monoclonal UCHL1 APC
anti-CD45RO (CD45RO) antibody (PE)GMP Grade (Analyte) CD45RO Reaktivität: Human FACS Wirt: Maus Monoclonal UCHL1 PE
anti-CD45RO (CD45RO) antibody (PE-CF®594)GMP Grade (Analyte) CD45RO Reaktivität: Human FACS Wirt: Maus Monoclonal UCHL1 PE-CF®594
anti-CD45RO (CD45RO) antibody (FITC)CD45RO Reaktivität: Human FACS, IHC (p), IHC, IP, IHC (fro) Wirt: Maus Monoclonal UCHL1 FITC
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Applikationshinweise
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IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 05:10:00
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 50 μg/mL
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Buffer
- Phosphate Buffered Saline (PBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- CD45RO
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Andere Bezeichnung
- CD45RO
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Hintergrund
- Background: CD45RO is also known as protein tyrosine phosphatase receptor type C (PTPRC). It is a protein tyrosine phosphatase required for T-cell activation through the antigen receptor. CD45RO acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45RO recruits and dephosphorylates SKAP1 and FYN. It also dephosphorylates LYN, and thereby modulates LYN activity (By similarity)[taken from UniProtKB (Entry: P08575)].
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Gen-ID
- 5788
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NCBI Accession
- NP_002829
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UniProt
- P08575
Target
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