CD45RO Antikörper

Produktnummer ABIN7449553

Dieser Maus Monoklonal Antikörper erkennt spezifisch CD45RO in FACS, IHC, WB, IF (p), ICC und mIF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD45RO Antikörper (ABIN7449553)

Target: CD45RO

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD45RO Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Multiplex Immunofluorescence (mIF)

Klon: UCHL-1

Produktdetails anti-CD45RO Antikörper

Verwendungszweck: Mouse anti-CD45RO Monoclonal Antibody Purified [UCHL-1]

Aufreinigung: Purified

Immunogen: Cultured T-cells from an IL-2-dependent T-cell line (CA1)

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 05:10:00

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 50 μg/mL

Buffer: Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2 - 8 °C

Haltbarkeit: 12 months

Details zu CD45RO

Target: CD45RO

Andere Bezeichnung: CD45RO

Hintergrund: CD45 is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. CD45 acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45 recruits and dephosphorylates SKAP1 and FYN [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P08575].

Gen-ID: 5788

UniProt: P08575