Rekombinanter CD56 Antikörper (AA 20-318)
Kurzübersicht für Rekombinanter CD56 Antikörper (AA 20-318) (ABIN7449431)
Target
Alle CD56 (NCAM1) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 20-318
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Verwendungszweck
- Rabbit anti-NCAM-1/CD56 Recombinant Monoclonal Antibody [BLR152J]
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Immunogen
- residues 20-318 (ECD)
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 01:01,00
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 100 μg/mL
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Buffer
- Phosphate Buffered Saline (PBS) containing 0.2 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
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Andere Bezeichnung
- NCAM-1/CD56
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Hintergrund
- Background: NCAM1, is a cell adhesion protein of the immunoglobulin superfamily that is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. It plays a role in the development of the nervous system by regulating neurogenesis, neurite outgrowth, and cell migration. NCAM1 is also involved in the expansion of T lymphocytes, B lymphocytes and natural killer (NK) cells which play an important role in immune surveillance. One prominent isoform NCAM1, known as cell surface molecule CD56, plays a role in several myeloproliferative disorders such as acute myeloid leukemia and differential expression of this gene is associated with differential disease progression. For example, increased expression of CD56 is correlated with lower survival in acute myeloid leukemia patients. [taken from NCBI Entrez Gene (Gene ID: 4684)].
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Gen-ID
- 4684
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NCBI Accession
- NP_000606
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UniProt
- P13591
Target
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