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Rekombinanter CD16 Antikörper (AA 21-201)

Dieses Anti-CD16-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von CD16 in WB, IHC und ICC. Geeignet für Human.
Produktnummer ABIN7449423

Kurzübersicht für Rekombinanter CD16 Antikörper (AA 21-201) (ABIN7449423)

Target

Alle CD16 Antikörper anzeigen
CD16

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 160
  • 31
  • 21
  • 21
  • 21
  • 9
  • 9
  • 8
  • 8
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Human

Wirt

  • 144
  • 27
  • 20
  • 1
Kaninchen

Klonalität

  • 164
  • 26
  • 1
Monoklonal

Konjugat

  • 68
  • 19
  • 15
  • 14
  • 9
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD16 Antikörper ist unkonjugiert

Applikation

  • 157
  • 36
  • 32
  • 28
  • 28
  • 25
  • 22
  • 21
  • 6
  • 6
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Klon

BLR163J
  • Bindungsspezifität

    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-201

    Verwendungszweck

    Rabbit anti-CD16 Recombinant Monoclonal Antibody [BLR163J]

    Immunogen

    residues 21-201 (ECD)

    Isotyp

    IgG
  • Applikationshinweise

    IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 01:01,00

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    100 μg/mL

    Buffer

    Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Haltbarkeit

    12 months
  • Target

    CD16

    Andere Bezeichnung

    CD16

    Hintergrund

    Background: CD16A (FCGR3A) is a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. CD16A is highly similar to another nearby gene (CD16B, FCGR3B) located on chromosome 1. CD16A is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas CD16B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. [taken from NCBI Entrez Gene (Gene ID: 2214)].

    Gen-ID

    2214, 2215

    NCBI Accession

    NP_000560

    UniProt

    P08637, O75015

    Pathways

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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