PDE12 Antikörper (AA 559-609)
Kurzübersicht für PDE12 Antikörper (AA 559-609) (ABIN7449244)
Target
Alle PDE12 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 559-609
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Verwendungszweck
- Rabbit anti-PDE12 Antibody, Affinity Purified
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Homologie
- Mouse,Rat,Bovine
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 559 and 609
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Isotyp
- IgG
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Applikationshinweise
- 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- PDE12 (Phosphodiesterase 12 (PDE12))
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Andere Bezeichnung
- PDE12
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Hintergrund
- Background: PDE12 is an enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. It also cleaves 3',5'-phosphodiester bond of oligoadenylates and plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system [taken from the Universal Protein Resource (UniProt) Q6L8Q7].
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Gen-ID
- 201626
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UniProt
- Q6L8Q7
Target
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