FLG2 Antikörper (AA 100-150)
Kurzübersicht für FLG2 Antikörper (AA 100-150) (ABIN7449193)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 100-150
-
Verwendungszweck
- Rabbit anti-FLG2 Antibody, Affinity Purified
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 100 and 150
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- 1:10,000 - 1:25,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- FLG2 (Filaggrin Family Member 2 (FLG2))
-
Andere Bezeichnung
- FLG2
-
Hintergrund
- Background: The FLG2 protein is upregulated by calcium, proteolyzed by calpain 1, and is involved in epithelial homeostasis. FLG2 is also required for proper cornification in skin, with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact, in addition to providing a physical barrier, C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa. [provided by RefSeq, Dec 2015] [taken from NCBI Entrez Gene (Gene ID: 388698)].
-
Gen-ID
- 388698
-
UniProt
- Q5D862
Target
-