This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Haltbarkeit
12 months
Target
Envoplakin (EVPL)
Andere Bezeichnung
EVPL
Hintergrund
Background: Envoplakin is a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. The gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated with both familial and sporadic forms of oesophageal squamous cell carcinoma. Patients suffering from the autoimmune mucocutaneous disorder, paraneoplastic pemphigus, develop antibodies against Envoplakin [taken from NCBI Entrez Gene (Gene ID: 2125)].