RBBP5 Antikörper (C-Term)
Kurzübersicht für RBBP5 Antikörper (C-Term) (ABIN7449051)
Target
Alle RBBP5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Rabbit anti-RbBP5 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 500 and C-term
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
ICC: 1:250 - 1:1,000
WB: 1:10,000 - 1:25,000
ChIP: 1 - 3 μg as per Dou et al., Nat Struct Mol Biol 13 (8):713-719, 2006. Previous lots of this antibody have performed in this application.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- RBBP5 (Retinoblastoma Binding Protein 5 (RBBP5))
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Andere Bezeichnung
- RbBP5
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Hintergrund
- Background: Retinoblastoma binding protein 5 (RbBP5) is a subunit of a human Set1-like histone methyltransferase (HMT) complex. The Set-1 like complexes are responsible for mono-, di-, and tri-methylation of histone H3 K4. RbBP5 associates with a multitude of proteins in a number of Set1-like complexes which include various combinations of MLL, MLL2, MLL3, MLL4, ASH2L,WDR5, hDPY-30, hSwd2, CXXC1, HCF1, Menin, PTIP, PA1, NCOA6, and UTX. RbBP5 is also one of many proteins that bind the Retinoblastoma tumor suppressor protein, pRb.
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Gen-ID
- 5929
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NCBI Accession
- NP_005048
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UniProt
- Q15291
Target
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