Fatty Acid Synthase Antikörper (AA 2462-2511)
Kurzübersicht für Fatty Acid Synthase Antikörper (AA 2462-2511) (ABIN7448964)
Target
Alle Fatty Acid Synthase (FASN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 2462-2511
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Verwendungszweck
- Rabbit anti-FASN IHC Antibody, Affinity Purified
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Homologie
- Rat,Goat,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Gray short-tailed opossum,Thirteen-lined ground squirrel,Chinese hamster,Naked mole rat,Northern white-cheeked gibbon,White-tufted-ear marmoset,Zebra finch,Tasmanian devil
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 2462 and 2511
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Isotyp
- IgG
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Applikationshinweise
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IHC-IF: 1:50 - 1:500
IHC: 1:100 - 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 250 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Fatty Acid Synthase (FASN)
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Andere Bezeichnung
- FASN
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Hintergrund
- Background: Fatty acid synthase (FASN) is a multifunctional protein that is mainly involved in catalyzing the synthesis of long-chain fatty acids. FASN has recently been viewed as an important protein involved in carcinogenesis as it has been found to be constitutively active in subsets of carcinomas and is associated with a poor prognosis. The inhibition of FASN activity in cancer cells promotes apoptosis and thus may play a role in maintaining cancer cell survival.
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Gen-ID
- 2194
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NCBI Accession
- NP_004095
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UniProt
- P49327
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Pathways
- AMPK Signaling
Target
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