This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Haltbarkeit
12 months
Target
WDFY3
(WD Repeat and FYVE Domain Containing 3 (WDFY3))
Andere Bezeichnung
WDFY3
Hintergrund
Background: WDFY3 (WD repeat and FYVE domain -containing protein 3) was identified in a screen for phosphatidylinositol -3-phosphate [PtdIns(3)P]- binding proteins. The FYVE domain is a zinc binding domain found in many PtdIns(3)-binding proteins and is proposed to target proteins to membrane lipids. WDFY3 has been shown localized to the nuclear membrane and within autophagic membranes and it is proposed to function as a link between protein aggregates and the autophagic machinery.