RNF20 Antikörper (AA 125-175)

Produktnummer ABIN7448779

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RNF20 in IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RNF20 Antikörper (AA 125-175) (ABIN7448779)

Target: RNF20 (Ring Finger Protein 20 (RNF20))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF20 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-RNF20 Antikörper

Bindungsspezifität: AA 125-175

Verwendungszweck: Rabbit anti-RNF20 IHC Antibody, Affinity Purified

Homologie: Mouse,Rat,Chicken,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Crab-eating macaque,White-tufted-ear marmoset,Tasmanian devil,Gray short-tailed opossum,Small-eared galago,Naked mole rat,Thirteen-lined ground squirrel,Chinese hamster,Northern white-cheeked gibbon,Green anole,Zebra finch,Ferret,Little brown bat

Aufreinigung: Affinity Purified

Immunogen: Between AA 125 and 175

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu RNF20

Target: RNF20 (Ring Finger Protein 20 (RNF20))

Andere Bezeichnung: RNF20

Hintergrund: Background: The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes, and the ligation of ubiquitin to the target protein by E3 enzymes. Ring finger protein 20 (RNF20) is a member of the RING type E3 ubiquitin ligases. RNF20 forms a complex with RNF40 to carry out H2B monoubiquitination in association with hPAF and the UbcH6 ubiquitin E2-conjugating enzyme. H2B monoubiquitination by RNF40/RNF20 has been shown to be associated with increased H3 methylation and gene transcription.

Gen-ID: 56254

NCBI Accession: NP_062538

UniProt: Q5VTR2