Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Importin Subunit alpha-1 in IHC. Es zeigt Reaktivität gegenüber Proben von Human und Maus.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Haltbarkeit
12 months
Target
Importin Subunit alpha-1 (KPNA2)
Andere Bezeichnung
RCH1/KPNA2
Hintergrund
Background: The import of proteins from the cytoplasm to the nucleus involves docking the protein to receptors associated with the nuclear pore complex followed by translocation through the nuclear pore. RCH1 is an adaptor protein that recognizes the nuclear localization signal (NLS) on cargo and binds the karyopherin importin-beta receptor for nuclear import which is regulated by RanGTP.