PML Antikörper (AA 375-425)
Kurzübersicht für PML Antikörper (AA 375-425) (ABIN7448728)
Target
Alle PML Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 375-425
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Verwendungszweck
- Rabbit anti-PML IHC Antibody, Affinity Purified
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Homologie
- Orangutan,Gorilla,Chimpanzee,Bornean orangutan,White-tufted-ear marmoset,Pygmy chimpanzee,Primates
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 375 and 425
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Isotyp
- IgG
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Applikationshinweise
- 1:100 - 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 100 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- PML (Promyelocytic Leukemia (PML))
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Andere Bezeichnung
- PML
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Hintergrund
- Background: PML is a member of RBCC/TRIM family of proteins that possess a RING finger domain, B-box, and coiled-coil domain. PML is a multifunctional protein involved in activities such as tumor growth suppression, hematopoietic differentiation, gene transcription, apoptotic induction, and viral immunity. PML is often involved in chromosomal translocations with the retinoic acid receptor alpha gene. PML-retinoic acid receptor translocations are associated with acute promyelocytic leukemia.
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Gen-ID
- 5371
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NCBI Accession
- NP_150241
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UniProt
- P29590
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Pathways
- p53 Signalweg, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
Target
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