PELP1 Antikörper (AA 1000-1050)

Produktnummer ABIN7448722

Produktdetails anti-PELP1 Antikörper

Target: PELP1 (Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1))

Bindungsspezifität: AA 1000-1050

Reaktivität: Maus, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PELP1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Verwendungszweck: Rabbit anti-PELP1/MNAR IHC Antibody, Affinity Purified

Homologie: Chimpanzee

Aufreinigung: Affinity Purified

Immunogen: Between AA 1000 and 1050

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu PELP1

Target: PELP1 (Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1))

Andere Bezeichnung: PELP1/MNAR (PELP1 Produkte)

Synonyme: MNAR antikoerper, P160 antikoerper, RGD1306320 antikoerper, 4930563C04Rik antikoerper, proline, glutamate and leucine rich protein 1 antikoerper, proline, glutamate and leucine rich protein 1 L homeolog antikoerper, proline, glutamic acid and leucine rich protein 1 antikoerper, PELP1 antikoerper, Pelp1 antikoerper, pelp1.L antikoerper

Hintergrund: Background: PELP1/MNAR was identified as an SH2 domain interacting protein that interacts with Lck, c-Src, and other members of the Src kinase family. PELP1/MNAR appears to function as a general coregulator and interacts with multiple nuclear receptors and transcription factors. PELP1/MNAR has also been shown to participate in nongenomic signaling via an association with a multiprotein complex, the ""signalsome"" involving ERalpha, Src kinase, PI3K, SHC, and G-proteins. As a transcriptional coregulator and signaling protein, PELP/MNAR mediates a variety of cellular functions such as cell proliferation, apoptosis, differentiation, oncogenesis and metastasis.

Gen-ID: 27043

UniProt: Q8IZL8