PAGR1 Antikörper (AA 204-254)

Produktnummer ABIN7448711

Der Kaninchen Polyklonal Anti-PAGR1-Antikörper wurde für IHC validiert. Er ist geeignet, PAGR1 in Proben von Human zu detektieren.

Kurzübersicht für PAGR1 Antikörper (AA 204-254) (ABIN7448711)

Target: PAGR1 (PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAGR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-PAGR1 Antikörper

Bindungsspezifität: AA 204-254

Verwendungszweck: Rabbit anti-PA1 IHC Antibody, Affinity Purified

Homologie: Horse,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Little brown bat,Small-eared galago,African elephant,Chinese hamster,Thirteen-lined ground squirrel,White-tufted-ear marmoset

Aufreinigung: Affinity Purified

Immunogen: Between AA 204 and 254

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu PAGR1

Target: PAGR1 (PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1))

Andere Bezeichnung: PA1

Hintergrund: Background: PA1 (PTIP-associated protein 1) was isolated as a protein that associates with PTIP (Pax transactivation domain-interacting protein), a nuclear protein involved in the DNA damage response and interacts with the Pax2 transactivation domain. Along with PTIP, PA1 has been found to be present in a MLL3- and MLL4-containing Histone H3 Lysine 4 Methyltransferase complex. PA1 also appears to be important to the DNA damage response and repair. This involvement in DNA damage signaling is reported to be independent of its MLL association. PA1 has also been identified as GAS (glutamate-rich coactivator interacting with SRC1/NCOA1). As an interactor of SRC1 (steroid receptor coactivator 1), PA1 functions as a transcription cofactor.

Gen-ID: 79447

NCBI Accession: NP_078792

UniProt: Q9BTK6