MED12 Antikörper (C-Term)

Produktnummer ABIN7448660

Der Kaninchen Polyklonal Anti-MED12-Antikörper wurde für IHC validiert. Er ist geeignet, MED12 in Proben von Human und Maus zu detektieren.

Kurzübersicht für MED12 Antikörper (C-Term) (ABIN7448660)

Target: MED12 (Mediator Complex Subunit 12 (MED12))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED12 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-MED12 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Rabbit anti-MED12 IHC Antibody, Affinity Purified

Homologie: Rat,Bovine,Dog,Pig,Panda,Orangutan,Monkey,Chimpanzee,Bornean orangutan,Crab-eating macaque,Thirteen-lined ground squirrel,Small-eared galago,Naked mole rat,White-tufted-ear marmoset,Northern white-cheeked gibbon,Little brown bat

Aufreinigung: Affinity Purified

Immunogen: Between AA 2150 and C-term

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu MED12

Target: MED12 (Mediator Complex Subunit 12 (MED12))

Andere Bezeichnung: MED12

Hintergrund: Background: MED12 is a component of the multisubunit mediator complex that functions as an interface between gene-specific transcription factors and the RNA Pol II/general transcription factor machinery. The mediator complex was first identified as a coactivator of the thyroid hormone receptor and has since been observed to function as a coactivator of a variety of transcription factors. In this context, MED12 interaction with beta-catenin has been shown to be required for Wnt-signaling dependent transcription.

Gen-ID: 9968

NCBI Accession: NP_005111

UniProt: Q93074

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation