MED1 Antikörper (C-Term)

Produktnummer ABIN7448659

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MED1 in IHC. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für MED1 Antikörper (C-Term) (ABIN7448659)

Target: MED1 (Mediator Complex Subunit 1 (MED1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-MED1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Rabbit anti-MED1 IHC Antibody, Affinity Purified

Homologie: Rat,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,African elephant,West Indian ocean coelacanth,Gray short-tailed opossum,Small-eared galago,Northern white-cheeked gibbon,Naked mole rat,Thirteen-lined ground squirrel,Chinese hamster,White-tufted-ear marmoset,Little brown bat,Zebra finch

Aufreinigung: Affinity Purified

Immunogen: Between AA 1525 and C-term

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu MED1

Target: MED1 (Mediator Complex Subunit 1 (MED1))

Andere Bezeichnung: MED1

Hintergrund: Background: MED1 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors [taken from the Universal Protein Resource (UniProt) Q15648].

Gen-ID: 5469

NCBI Accession: NP_004765

UniProt: Q15648

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha