CHD3 Antikörper (AA 1950-2000)
Kurzübersicht für CHD3 Antikörper (AA 1950-2000) (ABIN7448475)
Target
Alle CHD3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1950-2000
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Verwendungszweck
- Rabbit anti-CHD3 IHC Antibody, Affinity Purified
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Homologie
- Rat,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,White-tufted-ear marmoset,Naked mole rat,Little brown bat,Chinese hamster,Tasmanian devil,Gray short-tailed opossum,Small-eared galago
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 1950 and 2000
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Isotyp
- IgG
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Applikationshinweise
- 1:100 - 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 250 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))
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Andere Bezeichnung
- CHD3
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Hintergrund
- Background: CHD3 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD3 is a key component of the NuRD (nucleosomal remodeling) complex and directly interacts with histone deacetylases 1 and 2, ATR, and TRIM 27. Studies in several species suggest a role for CHD3 in the repression of developmental genes.
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Gen-ID
- 1107
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NCBI Accession
- NP_001005273
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UniProt
- Q12873
Target
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