Rat,Bovine,Horse,Rabbit,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Small-eared galago,Crab-eating macaque,Northern white-cheeked gibbon,Little brown bat,Naked mole rat
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Haltbarkeit
12 months
Target
ANKRD28
(Ankyrin Repeat Domain 28 (ANKRD28))
Andere Bezeichnung
ANKRD28/PITK
Hintergrund
Background: ANKRD28/PITK is a regulatory subunit of protein phosphatase-1 (PP1) that targets the PP1 catalytic subunit to nuclear foci to dephosphorylate and modulate the transcriptional activity of heterogeneous nuclear ribonucleoprotein K (hnRNPK). ANKRD28/PITK has been shown to be phosphorylated and regulated by calcium/calmodulin-dependent kinase II-delta (CaMKIIdelta) and glycogen synthase kinase-3 (GSK3).