Recombinant antibody expressed in mammalien cells and purified.
Güteklasse
Research Grade
Isotyp
IgG2 lambda
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS pH 7.5
Lagerung
-80 °C
Informationen zur Lagerung
store at -80°C
Target
PCSK9 (Evolocumab Biosimilar)
Substanzklasse
Biosimilar
Hintergrund
AMG 145,Anti-PCSK9 Evolocumab is a human IgG2 monoclonal antibody that binds to and prevents the binding of the proprotein convertase subtilisin/kexin type 9 (PCSK9). PCSK9 is a protein that binds to LDL receptors for degradation, thus reducing the liver’s activity of removal of LDL-cholesterol (LDL-C) from the blood. It is used in the treatment of hyperlipidemia.