Rekombinanter MS4A1 (Ibritumomab Biosimilar) Antikörper

Produktnummer ABIN7488261

Dieser Mammalian Cells Monoklonal Antikörper detektiert spezifisch MS4A1 (Ibritumomab Biosimilar) in ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter MS4A1 (Ibritumomab Biosimilar) Antikörper (ABIN7488261)

Target: MS4A1 (Ibritumomab Biosimilar)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Mammalian Cells

Klonalität: Monoklonal

Konjugat: Dieser MS4A1 (Ibritumomab Biosimilar) Antikörper ist unkonjugiert

Applikation: ELISA

Güteklasse: Research Grade

Produktdetails anti-MS4A1 (Ibritumomab Biosimilar) Antikörper

Expressionssystem: Mammalian cells

Verwendungszweck: Ibritumomab Biosimilar - Anti-MS4A1(CD20,MS4A-1) mAb

Produktmerkmale: Antibody Type: Human IgG2A

Aufreinigung: Recombinant antibody expressed in mammalien cells and purified.

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS pH 7.5

Lagerung: -80 °C

Informationen zur Lagerung: store at -80°C

Details zu MS4A1 (Ibritumomab Biosimilar)

Target: MS4A1 (Ibritumomab Biosimilar)

Substanzklasse: Biosimilar

Hintergrund: Ibritumomab is a monoclonal antibody directed against the CD20 antigen found on pre-B and mature B lymphocytes (normal and malignant). Ibritumomab binding induces apoptosis in B lymphocytes in vitro. It is combined with the chelator tiuxetan, which acts as a specific chelation site for Yttrium-90 (Y-90). The monoclonal antibody acts as a delivery system to direct the radioactive isotope to the targeted cells, however, binding has been observed in lymphoid cells throughout the body and in lymphoid nodules in organs such as the large and small intestines. beta-emission induces cellular damage through the formation of free radicals (in both target cells and surrounding cells).