s100a4 Antikörper

Produktnummer ABIN7384491

Der Kaninchen Monoklonal Anti-s100a4-Antikörper wurde für WB, IF und IHC (p) validiert. Er ist geeignet, s100a4 in Proben von Human zu detektieren.

Kurzübersicht für s100a4 Antikörper (ABIN7384491)

Target: s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser s100a4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: R01-7H1

Produktdetails anti-s100a4 Antikörper

Aufreinigung: Affinity Purified

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:2000 IHC 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu s100a4

Target: s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))

Andere Bezeichnung: S100A4

Hintergrund: 18A2,42A,calcium Placental protein,Calvasculin,CAPL,Fibroblast specific protein 1 (FSP1),Fibroblast specific protein 1,Fibroblast specific protein,FSP1,Leukemia multidrug resistance associated protein,Malignant transformation suppression 1 (MTS1),Malignant transformation suppression 1,Metastasin,MTS1,OTTHUMP00000015467,OTTHUMP00000015468,P9KA,PEL98,Placental calcium-binding protein,Protein Mts1,Protein S100 A4,Protein S100-A4,S100 calcium binding protein A4 (calcium protein,calvasculin,metastasin,murine placental homolog),S100 calcium binding protein A4,S100 calcium-binding protein A4,S100a4,S10A4,S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.

Molekulargewicht:

Observed_MW: 12kDa

Calculated_MW: 12kDa

Gen-ID: 6275

UniProt: P26447

Pathways: S100 Proteine