Integrin beta 5 Antikörper

Produktnummer ABIN7384459

Produktdetails anti-Integrin beta 5 Antikörper

Target: Integrin beta 5 (ITGB5)

Reaktivität: Human, Ratte, Hamster

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Integrin beta 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity Purified

Klon: R04-0G6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Integrin beta 5

Target: Integrin beta 5 (ITGB5)

Andere Bezeichnung: Integrin beta 5 (ITGB5 Produkte)

Hintergrund: FLJ26658,Integrin beta-5,Integrin subunit beta 5,integrin,beta 5,ITB5,Itgb5,Testis secretory sperm-binding protein Li 217p,Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors, both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. 

Molekulargewicht:

Observed_MW: 88kDa

Calculated_MW: 88kDa

Gen-ID: 3693

UniProt: P18084

Pathways: Integrin Complex