Cofilin Antikörper
Kurzübersicht für Cofilin Antikörper (ABIN7384433)
Target
Alle Cofilin (CFL1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Affinity Purified
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 300 μg/mL
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Buffer
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cofilin (CFL1) (Cofilin 1 (CFL1))
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Andere Bezeichnung
- Cofilin
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Hintergrund
- 18 kDa phosphoprotein,CFL 1,CFL,CFL1,COF1,Cofilin 1,Cofilin 1 non muscle,Cofilin,Cofilin non muscle isoform,Cofilin-1,epididymis secretory protein Li 15,HEL-S-15,non-muscle isoform,p18,Cofilin is a ubiquitous actin-binding protein required for the reorganization of actin filaments. It is a member of ADF (actin-depolymerizing factor)/cofilin family that is a key regulator of actin dynamics and essential for cellular motility,cytokinesis,and endocytosis. Cofilin activity is tightly regulated by phosphorylation and dephosphorylation. Phosphorylation at Ser3 can inhibit its activity,also causing translocation from the nucleus to the cytoplasm.
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Molekulargewicht
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Observed_MW: 19kDa
Calculated_MW: 19kDa
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Gen-ID
- 1072
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UniProt
- P23528
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Pathways
- Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
Target
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