SMG7 Antikörper

Produktnummer ABIN7384099

Dieses Anti-SMG7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SMG7 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für SMG7 Antikörper (ABIN7384099)

Target: SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMG7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SMG7 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human SMG7 (NP_963863.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SMG7

Target: SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))

Andere Bezeichnung: SMG7

Hintergrund: SMG7,C1orf16,EST1C,SGA56M,This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD), a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht:

Observed_MW: 127 kDa

Calculated_MW: 122 kDa/127 kDa/131 kDa

Gen-ID: 9887

UniProt: Q92540