EEF1E1 Antikörper

Produktnummer ABIN7384097

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch EEF1E1 in WB und IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für EEF1E1 Antikörper (ABIN7384097)

Target: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EEF1E1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-EEF1E1 Antikörper

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human EEF1E1 (NP_004271.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200-1:2000 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EEF1E1

Target: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Andere Bezeichnung: EEF1E1

Hintergrund: EEF1E1,AIMP3,P18,This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.

Molekulargewicht:

Observed_MW: 20 kDa

Calculated_MW: 15 kDa/19 kDa

Gen-ID: 9521

UniProt: O43324

Pathways: Positive Regulation of Response to DNA Damage Stimulus