EEF1E1 Antikörper

Produktnummer ABIN7384097

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch EEF1E1 in WB und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für EEF1E1 Antikörper (ABIN7384097)

Target: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EEF1E1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-EEF1E1 Antikörper

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human EEF1E1 (NP_004271.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200-1:2000 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EEF1E1

Target: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Andere Bezeichnung: EEF1E1

Hintergrund: EEF1E1,AIMP3,P18,This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.

Molekulargewicht:

Observed_MW: 20 kDa

Calculated_MW: 15 kDa/19 kDa

Gen-ID: 9521

UniProt: O43324

Pathways: Positive Regulation of Response to DNA Damage Stimulus