AGXT Antikörper

Produktnummer ABIN7384024

Produktdetails anti-AGXT Antikörper

Target: AGXT (Alanine Glyoxylate Aminotransferase (AGXT))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGXT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human AGXT

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu AGXT

Target: AGXT (Alanine Glyoxylate Aminotransferase (AGXT))

Andere Bezeichnung: AGXT (AGXT Produkte)

Synonyme: AGT antikoerper, AGT1 antikoerper, AGXT1 antikoerper, PH1 antikoerper, SPAT antikoerper, SPT antikoerper, TLH6 antikoerper, Spat antikoerper, Agt1 antikoerper, Agxt1 antikoerper, agt antikoerper, agt1 antikoerper, agxt antikoerper, agxt1 antikoerper, spt antikoerper, agxtl antikoerper, zgc:91879 antikoerper, wu:fb57d01 antikoerper, zgc:65930 antikoerper, alanine-glyoxylate aminotransferase antikoerper, serine--pyruvate aminotransferase, mitochondrial antikoerper, alanine-glyoxylate aminotransferase L homeolog antikoerper, alanine-glyoxylate aminotransferase a antikoerper, alanine-glyoxylate aminotransferase b antikoerper, AGXT antikoerper, Agxt antikoerper, LOC607355 antikoerper, agxt.L antikoerper, agxta antikoerper, agxtb antikoerper

Hintergrund: AGT,AGT1,Agxt,AGXT1,Alanine glyoxylate aminotransferase,Alanine glyoxylate aminotransferase3,Alanine--glyoxylate aminotransferase,EC 2.6.1.44,EC 2.6.1.51,Hepatic peroxisomal alanine glyoxylate aminotransferase,Hepatic peroxisomal alanine:glyoxylate aminotransferase,L alanine glyoxylate aminotransferase 1,MS773,PH1,Serine pyruvate aminotransferase,Serine--pyruvate aminotransferase,Serine--pyruvate aminotransferase,mitochondrial,Serine:pyruvate aminotransferase,SPAT,SPT,SPYA,TLH6,Serine-pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene. This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1), also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.

Molekulargewicht: 43 kDa

NCBI Accession: NP_000021

UniProt: P21549

Pathways: Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport