LRPAP1 Antikörper

Produktnummer ABIN7383949

Dieses Anti-LRPAP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LRPAP1 in WB, IHC und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für LRPAP1 Antikörper (ABIN7383949)

Target: LRPAP1 (Low Density Lipoprotein Receptor-Related Protein Associated Protein 1 (LRPAP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRPAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-LRPAP1 Antikörper

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human LRPAP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LRPAP1

Target: LRPAP1 (Low Density Lipoprotein Receptor-Related Protein Associated Protein 1 (LRPAP1))

Andere Bezeichnung: LRPAP1

Hintergrund: 39 kDa receptor-associated protein,A2MRAP,A2RAP,Alpha 2 macroglobulin receptor associated protein,Alpha 2 MRAP,Alpha-2-macroglobulin receptor-associated protein,Alpha-2-MRAP,AMRP,HBP44,Lipoprotein receptor associated protein,Low density lipoprotein receptor related protein associated protein 1,Low density lipoprotein receptor-related protein-associated protein 1,Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein,Low density lipoprotein related protein associated protein 1,low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1),Lrpap1,MGC138272,MRAP,MYP23,RAP,Low density lipoprotein receptor-related protein associated protein 1also known asLRPAP1orRAPis a chaperoneproteinwhich in humans is encoded by the LRPAP1gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II.

Molekulargewicht: 41 kDa

NCBI Accession: NP_002328

UniProt: P30533