SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N) Antikörper

Produktnummer ABIN7383874

Produktdetails

Target: SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N)

Reaktivität: SARS Coronavirus (SARS-CoV)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Spezifität: Anti-SARS-CoV Nucleoprotein / NP Monoclonal Antibody

Aufreinigung: Protein A Affinity

Immunogen: Recombinant SARS-CoV Nucleoprotein/NP Protein (His Tag),PKSV030248

Klon: 8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:5000 ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 0.2 μm filtered solution in PBS

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Antigendetails

Target: SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N)

Andere Bezeichnung: SARS-CoV Nucleoprotein / NP (SARS-CoV N Produkte)

Hintergrund: Coronavirus NP,coronavirus Nucleocapsid,coronavirus Nucleoprotein,cov np,ncov NP,novel coronavirus NP,novel coronavirus Nucleocapsid,novel coronavirus Nucleoprotein,NP,Nucleocapsid,Nucleoprotein,Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.