SARS-CoV-2 NSP1 Antikörper

Produktnummer ABIN7272996

Der Ziege Polyklonal anti-SARS-CoV-2 NSP1 Antikörper wird verwendet zum Nachweis von SARS-CoV-2 NSP1 in Proben von SARS Coronavirus-2 (SARS-CoV-2). Er wurde validiert für WB.

Kurzübersicht für SARS-CoV-2 NSP1 Antikörper (ABIN7272996)

Target: SARS-CoV-2 NSP1 (SARS-CoV-2 Host Translation Inhibitor Nsp1 (SARS-CoV-2 NSP1))

Reaktivität: SARS Coronavirus-2 (SARS-CoV-2)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser SARS-CoV-2 NSP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SARS-CoV-2 NSP1 Antikörper

Verwendungszweck: anti-NSP1 (SARS-CoV-2)

Sequenz: MESLVPGFNE KTHVQLSLPV LQVRDVLVRG FGDSVEEVLS EARQHLKDGT CGLVEVEKGV LPQLEQPYVF IKRSDARTAP HGHVMVELVA ELEGIQYGRS GETLGVLVPH VGEIPVAYRK VLLRKNGNKG AGGHSYGADL KSFDLGDELG TDPYEDFQEN WNTKHSSGVT RELMRELNGG

Spezifität: In lysates of transfected cells with the plasmid containing the sequence used, detects the fusion protein by Western blot.

Kreuzreaktivität (Details): Reacts with SARS-CoV-2 protein

Aufreinigung: Epitope affinity purified

Immunogen: Affinity purified recombinant fusion protein Nsp1 of SARS-CoV-2 produced in E. coli.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:2,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 3 mg/mL

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: The antibody solution should be gently mixed before use.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Details zu SARS-CoV-2 NSP1

Target: SARS-CoV-2 NSP1 (SARS-CoV-2 Host Translation Inhibitor Nsp1 (SARS-CoV-2 NSP1))

Andere Bezeichnung: NSP1 (SARS-CoV-2)

Substanzklasse: Viral Protein

Hintergrund:

Host translation inhibitor Nsp1 is part of the multifunctional protein replicase polyprotein 1ab that is involved in the transcription and replication of viral RNA. NSP1 inhibits the host translation by interacting with the 40S ribosomal subunit. The nsp1-40S ribosome complex further induces an endonucleolytic cleavage near the 5'UTR of host mRNAs, targeting them for degradation. Therefore, Nsp1 facilitates efficient viral gene expression in infected cells and evasion from host immune response by suppressing host gene expression.

Host translation inhibitor, Nsp1 SARS Coronavirus-2 antibody.