CD16 Antikörper
Kurzübersicht für CD16 Antikörper (ABIN7271861)
Target
Alle CD16 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- CD16 Unconjugated Antibody
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Produktmerkmale
- Alternative clone name HuNK2, the clone C-4H1G, a mouse monoclonal antibody binds to the 50-65 kDa transmembrane protein of IgG FcγRIII known as CD16, a surface antigen commonly associated with human NK cells. In addition to surface expression on NK cells, CD16 is expressed on activated monocytes, macrophages, neutrophils, and placental trophoblasts in humans. C-4H1G has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils.
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Aufreinigung
- Purified
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Reinheit
- >95 %
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Immunogen
- Human peripheral blood T lymphocytes from a NK-leukemia patient
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Isotyp
- IgG2a, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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- CD16
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Andere Bezeichnung
- CD16
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Gen-ID
- 2214
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UniProt
- Q92835
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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