Rekombinanter SARS-CoV-2 Spike Antikörper (RBD)

Produktnummer ABIN7271755

Dieses Human Monoklonal-Antikörper erkennt spezifisch SARS-CoV-2 Spike in Neut. Er zeigt eine Reaktivität gegenüber SARS Coronavirus-2 (SARS-CoV-2).

Kurzübersicht für Rekombinanter SARS-CoV-2 Spike Antikörper (RBD) (ABIN7271755)

Target: SARS-CoV-2 Spike

Antikörpertyp: Recombinant Antibody

Reaktivität: SARS Coronavirus-2 (SARS-CoV-2)

Wirt: Human

Klonalität: Monoklonal

Konjugat: Dieser SARS-CoV-2 Spike Antikörper ist unkonjugiert

Applikation: Neutralization (Neut)

Güteklasse: MALS verified

Klon: AM359b

Produktdetails anti-SARS-CoV-2 Spike Antikörper

Bindungsspezifität: RBD

Verwendungszweck: Anti-SARS-CoV-2 Spike RBD Broadly Neutralizing Antibody, Human IgG4 (AM359b) (MALS verified)

Spezifität: This product is a specific antibody specifically reacts with This product is a specific antibody against SARS-CoV-2 Spike protein RBD domain. Cross-reactivity with Spike protein RBD domain of other coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1 has not been tested.

Produktmerkmale: Recombinant Antibodies produced in HEK293. Anti-SARS-CoV-2 Spike RBD Broadly Neutralizing, Human IgG4 is isolated from a Spike RBD infected Human and is recombinantly produced from human 293 cells (HEK293)

Immunogen: The antibody is isolated from the serum of COVID-19 vaccine recipient and is recombinantly produced from human 293 cells (HEK293). This antibody can broadly neutralize SARS-CoV-2 Variants of Concerns (VOCs) including Alpha, Beta, Gamma, Delta and Omicron.

Isotyp: IgG4

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Powder

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu SARS-CoV-2 Spike

Target: SARS-CoV-2 Spike

Hintergrund: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.