Rekombinanter SARS-CoV-2 Spike Antikörper (RBD)

Produktnummer ABIN7271733

Dieses Anti-SARS-CoV-2 Spike-Antikörper ist ein Human Chimeric-Antikörper zur Detektion von SARS-CoV-2 Spike in . Geeignet für SARS Coronavirus-2 (SARS-CoV-2) und SARS CoV-2 Delta.

Kurzübersicht für Rekombinanter SARS-CoV-2 Spike Antikörper (RBD) (ABIN7271733)

Target: SARS-CoV-2 Spike

Antikörpertyp: Recombinant Antibody

Reaktivität: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Delta

Wirt: Human

Klonalität: Chimeric

Konjugat: Dieser SARS-CoV-2 Spike Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Klon: AM110

Produktdetails anti-SARS-CoV-2 Spike Antikörper

Bindungsspezifität: RBD

Verwendungszweck: Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM110) (Delta Specific)

Spezifität: This product is a specific antibody against SARS-CoV-2 Spike protein RBD domain. Cross-reactivity with Spike protein RBD domain of other coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1, has not been tested.

Produktmerkmale: Recombinant Antibodies produced in HEK293. Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (Delta Specific) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike RBD protein. The antibody is specific against the Delta (B.1.617.2/AY.4) variant of SARS-CoV-2, and has no binding with the spike RBD of the wild type virus and the Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), Omicron (B.1.1.529/BA.1) variant.

Immunogen: Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (Delta Specific) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike RBD protein. The antibody is specific against the Delta (B.1.617.2/AY.4) variant of SARS-CoV-2, and has no binding with the spike RBD of the wild type virus and the Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), Omicron (B.1.1.529/BA.1) variant.

Isotyp: IgG1

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Powder

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu SARS-CoV-2 Spike

Target: SARS-CoV-2 Spike

Hintergrund: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.