ZFX Antikörper (AA 180-380)
Kurzübersicht für ZFX Antikörper (AA 180-380) (ABIN7271539)
Target
Alle ZFX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 180-380
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Verwendungszweck
- ZFX Rabbit pAb
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Sequenz
- VLVADCASEA VIDANGIPVD QQDDDKGNCE DYLMISLDDA GKIEHDGSSG MTMDTESEID PCKVDGTCPE VIKVYIFKAD PGEDDLGGTV DIVESEPEND HGVELLDQNS SIRVPREKMV YMTVNDSQPE DEDLNVAEIA DEVYMEVIVG EEDAAAAAAA AAVHEQQMDD NEIKTFMPIA WAAAYGNNSD GIENRNGTAS A
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human ZFX (NP_003401.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- ZFX (Zinc Finger Protein, X-Linked (ZFX))
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Andere Bezeichnung
- ZFX
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Hintergrund
- This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined.,ZFX,ZNF926,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Stem Cells,Embryonic Stem Cells,Hematopoietic Progenitors,ZFX
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Molekulargewicht
- 66kDa/90kDa/94kDa
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Gen-ID
- 7543
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UniProt
- P17010
Target
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