ZNF384 Antikörper (AA 1-180)

Produktnummer ABIN7271478

Dieses Anti-ZNF384-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ZNF384 in WB und IHC. Geeignet für Human.

Kurzübersicht für ZNF384 Antikörper (AA 1-180) (ABIN7271478)

Target: ZNF384 (Zinc Finger Protein 384 (ZNF384))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF384 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ZNF384 Antikörper

Bindungsspezifität: AA 1-180

Verwendungszweck: ZNF384 Rabbit pAb

Sequenz: MEESHFNSNP YFWPSIPTVS GQIENTMFIN KMKDQLLPEK GCGLAPPHYP TLLTVPASVS LPSGISMDTE SKSDQLTPHS QASVTQNITV VPVPSTGLMT AALQVVPDLS KKVASTLTEE GGGGGGGGGS VAPKPPRGRK KKRMLESGLP EMNDPYVLSP EDDDDHQKDG KTYRCRMCSL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ZNF384 (NP_001035009.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ZNF384

Target: ZNF384 (Zinc Finger Protein 384 (ZNF384))

Andere Bezeichnung: ZNF384

Hintergrund: This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.,ZNF384,CAGH1,CAGH1A,CIZ,ERDA2,NMP4,NP,TNRC1,Epigenetics & Nuclear Signaling,Transcription Factors,ZNF384

Molekulargewicht: 50kDa/56kDa/63kDa

Gen-ID: 171017

UniProt: Q8TF68