UGT1A6 Antikörper (AA 65-270)
Kurzübersicht für UGT1A6 Antikörper (AA 65-270) (ABIN7271193)
Target
Alle UGT1A6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 65-270
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Verwendungszweck
- UGT1A6 Rabbit pAb
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Sequenz
- LLLKESKYYT RKIYPVPYDQ EELKNRYQSF GNNHFAERSF LTAPQTEYRN NMIVIGLYFI NCQSLLQDRD TLNFFKESKF DALFTDPALP CGVILAEYLG LPSVYLFRGF PCSLEHTFSR SPDPVSYIPR CYTKFSDHMT FSQRVANFLV NLLEPYLFYC LFSKYEELAS AVLKRDVDII TLYQKVSVWL LRYDFVLEYP RPVMPN
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 65-270 of human UGT1A6 (NP_001063.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))
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Andere Bezeichnung
- UGT1A6
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Hintergrund
- This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.,UGT1A6;GNT1;HLUGP;HLUGP1;UDPGT;UDPGT 1-6;UGT1;UGT1A6S;UGT1F;UDPGT1-6,Cancer,Signal Transduction,Endocrine & Metabolism,Drug metabolism,UGT1A6
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Molekulargewicht
- 29kDa/50kDa/60kDa
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Gen-ID
- 54578
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UniProt
- P19224
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Pathways
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
Target
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