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UGT1A6 Antikörper (AA 65-270)

Dieses Anti-UGT1A6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von UGT1A6 in WB und IF. Geeignet für Human.
Produktnummer ABIN7271193

Kurzübersicht für UGT1A6 Antikörper (AA 65-270) (ABIN7271193)

Target

Alle UGT1A6 Antikörper anzeigen
UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))

Reaktivität

  • 24
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 22
  • 3
Kaninchen

Klonalität

  • 23
  • 2
Polyklonal

Konjugat

  • 15
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser UGT1A6 Antikörper ist unkonjugiert

Applikation

  • 12
  • 10
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • Bindungsspezifität

    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 65-270

    Verwendungszweck

    UGT1A6 Rabbit pAb

    Sequenz

    LLLKESKYYT RKIYPVPYDQ EELKNRYQSF GNNHFAERSF LTAPQTEYRN NMIVIGLYFI NCQSLLQDRD TLNFFKESKF DALFTDPALP CGVILAEYLG LPSVYLFRGF PCSLEHTFSR SPDPVSYIPR CYTKFSDHMT FSQRVANFLV NLLEPYLFYC LFSKYEELAS AVLKRDVDII TLYQKVSVWL LRYDFVLEYP RPVMPN

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 65-270 of human UGT1A6 (NP_001063.2).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IF,1:50 - 1:100

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))

    Andere Bezeichnung

    UGT1A6

    Hintergrund

    This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.,UGT1A6;GNT1;HLUGP;HLUGP1;UDPGT;UDPGT 1-6;UGT1;UGT1A6S;UGT1F;UDPGT1-6,Cancer,Signal Transduction,Endocrine & Metabolism,Drug metabolism,UGT1A6

    Molekulargewicht

    29kDa/50kDa/60kDa

    Gen-ID

    54578

    UniProt

    P19224

    Pathways

    Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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