TMED10 Antikörper (AA 35-190)

Produktnummer ABIN7270945

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TMED10 in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TMED10 Antikörper (AA 35-190) (ABIN7270945)

Target: TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMED10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Güteklasse: KO Validated

Produktdetails anti-TMED10 Antikörper

Bindungsspezifität: AA 35-190

Verwendungszweck: [KO Validated] TMED10 Rabbit pAb

Sequenz: HLPINSRKCL REEIHKDLLV TGAYEISDQS GGAGGLRSHL KITDSAGHIL YSKEDATKGK FAFTTEDYDM FEVCFESKGT GRIPDQLVIL DMKHGVEAKN YEEIAKVEKL KPLEVELRRL EDLSESIVND FAYMKKREEE MRDTNESTNT RVLYFS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 35-190 of human TMED10 (NP_006818.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TMED10

Target: TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))

Andere Bezeichnung: TMED10

Hintergrund: This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.,TMED10,P24(DELTA),S31I125,S31III125,TMP21,Tmp-21-I,p23,p24d1,Signal Transduction,Cell Biology & Developmental Biology,Hippo Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,TMED10

Molekulargewicht: 24kDa

Gen-ID: 10972

UniProt: P49755