Translin Antikörper (AA 50-150)

Produktnummer ABIN7270923

Dieses Anti-Translin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Translin in WB, IHC und IF. Geeignet für Human.

Kurzübersicht für Translin Antikörper (AA 50-150) (ABIN7270923)

Target: Translin (TSN)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Translin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Translin Antikörper

Bindungsspezifität: AA 50-150

Verwendungszweck: TSN Rabbit pAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human TSN (NP_004613.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Translin

Target: Translin (TSN)

Andere Bezeichnung: TSN

Hintergrund: This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants.,BCLF-1,C3PO,RCHF1,REHF-1,TBRBP,TRSLN,TSN,translin,DNA Damage & Repair,Epigenetics & Nuclear Signaling,TSN

Molekulargewicht: 17kDa/26kDa

Gen-ID: 7247

UniProt: Q15631