TP53RK Antikörper (AA 1-253)

Produktnummer ABIN7270864

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TP53RK in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TP53RK Antikörper (AA 1-253) (ABIN7270864)

Target: TP53RK (TP53 Regulating Kinase (TP53RK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TP53RK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TP53RK Antikörper

Bindungsspezifität: AA 1-253

Verwendungszweck: TP53RK Rabbit pAb

Sequenz: MAAARATTPA DGEEPAPEAE ALAAARERSS RFLSGLELVK QGAEARVFRG RFQGRAAVIK HRFPKGYRHP ALEARLGRRR TVQEARALLR CRRAGISAPV VFFVDYASNC LYMEEIEGSV TVRDYIQSTM ETEKTPQGLS NLAKTIGQVL ARMHDEDLIH GDLTTSNMLL KPPLEQLNIV LIDFGLSFIS ALPEDKGVDL YVLEKAFLST HPNTETVFEA FLKSYSTSSK KARPVLKKLD EVRLRGRKRS MVG

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human TP53RK (NP_291028.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TP53RK

Target: TP53RK (TP53 Regulating Kinase (TP53RK))

Andere Bezeichnung: TP53RK

Hintergrund: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6A37 in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP to the N6 group of A37. TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP (By similarity. Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation.,TP53RK,BUD32,C20orf64,Nori-2,Nori-2p,PRPK,dJ101A2,Signal Transduction,Kinase,TP53RK

Molekulargewicht: 28kDa

Gen-ID: 112858

UniProt: Q96S44