TFPI Antikörper

Produktnummer ABIN7270831

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch TFPI in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TFPI Antikörper (ABIN7270831)

Target: TFPI (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser TFPI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TFPI Antikörper

Verwendungszweck: TFPI Rabbit mAb

Kreuzreaktivität: Human

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human TFPI

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TFPI

Target: TFPI (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))

Andere Bezeichnung: TFPI

Hintergrund: This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016],EPI, LACI, TFI, TFPI1,Blood,Blood_Coagulation,Cardiovascular,TFPI

Molekulargewicht: 35-45kDa

Gen-ID: 7035

UniProt: P10646