THBS4
Reaktivität: Human
WB, IHC, ICC, IP
Wirt: Maus
Monoclonal
unconjugated
Applikationshinweise
WB,1:500 - 1:2000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
THBS4
(Thrombospondin 4 (THBS4))
Andere Bezeichnung
THBS4
Hintergrund
The protein encoded by this gene belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. It is involved in local signaling in the developing and adult nervous system, and it contributes to spinal sensitization and neuropathic pain states. This gene is activated during the stromal response to invasive breast cancer. It may also play a role in inflammatory responses in Alzheimer's disease. Alternative splicing results in multiple transcript variants.,THBS4;TSP-4;TSP4,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Neuroscience,Calcium Signaling,Cardiovascular,Angiogenesis,Heart,Contractility,THBS4