TBC1D5 Antikörper (AA 446-795)

Produktnummer ABIN7270750

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TBC1D5 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TBC1D5 Antikörper (AA 446-795) (ABIN7270750)

Target: TBC1D5 (TBC1 Domain Family, Member 5 (TBC1D5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBC1D5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TBC1D5 Antikörper

Bindungsspezifität: AA 446-795

Verwendungszweck: TBC1D5 Rabbit pAb

Sequenz: NAKGAPLNIN KVSNSLINFG RKLISPAMAP GSAGGPVPGG NSSSSSSVVI PTRTSAEAPS HHLQQQQQQQ RLMKSESMPV QLNKGLSSKN ISSSPSVESL PGGREFTGSP PSSATKKDSF FSNISRSRSH SKTMGRKESE EELEAQISFL QGQLNDLDAM CKYCAKVMDT HLVNIQDVIL QENLEKEDQI LVSLAGLKQI KDILKGSLRF NQSQLEAEEN EQITIADNHY CSSGQGQGRG QGQSVQMSGA IKQASSETPG CTDRGNSDDF ILISKDDDGS SARGSFSGQA QPLRTLRSTS GKSQAPVCSP LVFSDPLMGP ASASSSNPSS SPDDDSSKDS GFTIVSPLDI

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 446-795 of human TBC1D5 (NP_055559.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TBC1D5

Target: TBC1D5 (TBC1 Domain Family, Member 5 (TBC1D5))

Andere Bezeichnung: TBC1D5

Hintergrund: May act as a GTPase-activating protein (GAP for Rab family protein(s. May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol, at least retromer displacement seems to require its catalytic activity. Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN, the function seems to require its catalytic activity. Involved in regulation of autophagy. May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming vesicle trafficking upon autophagy induction. Involved in the trafficking of ATG9A upon activation of autophagy. May regulate the recruitment of ATG9A-AP2-containing vesicles to autophagic membranes.,TBC1D5,TBC1D5

Molekulargewicht: 89kDa/91kDa

Gen-ID: 9779

UniProt: Q92609