TAX1BP3 Antikörper

Produktnummer ABIN7270742

Der Kaninchen Monoklonal Anti-TAX1BP3-Antikörper wurde für WB validiert. Er ist geeignet, TAX1BP3 in Proben von Human zu detektieren.

Kurzübersicht für TAX1BP3 Antikörper (ABIN7270742)

Target: TAX1BP3 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser TAX1BP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TAX1BP3 Antikörper

Verwendungszweck: TAX1BP3 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human TAX1BP3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TAX1BP3

Target: TAX1BP3 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3))

Andere Bezeichnung: TAX1BP3

Hintergrund: This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways, for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,TIP-1, TIP1,Epigenetics & Nuclear Signaling,G protein signaling,G protein signaling_Small G proteins,Signal Transduction,Stem Cells,TAX1BP3

Molekulargewicht: 14kDa

Gen-ID: 30851

UniProt: O14907

Pathways: Monocarboxylic Acid Catabolic Process