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SNCA Antikörper (AA 59-140)
SNCA
Reaktivität: Human
WB, IHC, IF
Wirt: Kaninchen
Monoclonal
unconjugated
Produktnummer ABIN7270695
Produktdetails anti-SNCA Antikörper
(ausblenden)
Target
Alle SNCA Antikörper anzeigen
SNCA
(Synuclein, alpha (SNCA))
Bindungsspezifität
Alle Epitope für SNCA Antikörper
AA 59-140
Reaktivität
Alle Reaktivitäten für SNCA Antikörper
Human
Wirt
Alle Wirte für SNCA Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für SNCA Antikörper
Monoklonal
Konjugat
Alle Konjugate für SNCA Antikörper
Dieser SNCA Antikörper ist unkonjugiert
Applikation
Alle Applikationen für SNCA Antikörper
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Verwendungszweck
α-Synuclein Rabbit mAb
Sequenz
EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA
Kreuzreaktivität
Human, Maus, Ratte
Produktmerkmale
Monoclonal Antibodies
Aufreinigung
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 59-140 of human alpha-Synuclein (NP_000336.1).
Isotyp
IgG
Top Product
Discover our top product SNCA Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Details zu SNCA
(ausblenden)
Target
SNCA
(Synuclein, alpha (SNCA))
Andere Bezeichnung
SNCA (SNCA Produkte )
Synonyme
snca antikoerper, MGC64356 antikoerper, LOC619283 antikoerper, NACP antikoerper, alphaSYN antikoerper, PARK1 antikoerper, PARK4 antikoerper, PD1 antikoerper, synuclein alpha L homeolog antikoerper, alpha-synuclein antikoerper, synuclein alpha antikoerper, synuclein, alpha antikoerper, snca.L antikoerper, LOC619283 antikoerper, SNCA antikoerper, Snca antikoerper
Hintergrund
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.,PD1,NACP,PARK1,PARK4,SNCA,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Dopamine Signaling in Parkinson's Disease,Neurodegenerative Diseases Markers,SNCA
Molekulargewicht
11kDa/13kDa/14kDa
Gen-ID
6622
UniProt
P37840
Pathways
Synaptic Membrane , Regulation of G-Protein Coupled Receptor Protein Signaling , Positive Regulation of Endopeptidase Activity , Regulation of Carbohydrate Metabolic Process , Platelet-derived growth Factor Receptor Signaling , Negative Regulation of Transporter Activity , Regulation of long-term Neuronal Synaptic Plasticity
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