Syntaxin 17 Antikörper (AA 1-130)
Kurzübersicht für Syntaxin 17 Antikörper (AA 1-130) (ABIN7270682)
Target
Alle Syntaxin 17 (STX17) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-130
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Verwendungszweck
- STX17 Rabbit pAb
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Sequenz
- MSEDEEKVKL RRLEPAIQKF IKIVIPTDLE RLRKHQINIE KYQRCRIWDK LHEEHINAGR TVQQLRSNIR EIEKLCLKVR KDDLVLLKRM IDPVKEEASA ATAEFLQLHL ESVEELKKQF NDEETLLQPP
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Kreuzreaktivität
- Human, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human STX17 (NP_060389.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Syntaxin 17 (STX17)
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Andere Bezeichnung
- STX17
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Hintergrund
- SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi.,STX17,Signal Transduction,STX17
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Gen-ID
- 55014
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UniProt
- P56962
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Pathways
- Synaptic Vesicle Exocytosis
Target
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