SPRY2 Antikörper (AA 1-100)

Produktnummer ABIN7270555

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SPRY2 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SPRY2 Antikörper (AA 1-100) (ABIN7270555)

Target: SPRY2 (Sprouty Homolog 2 (SPRY2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPRY2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SPRY2 Antikörper

Bindungsspezifität: AA 1-100

Verwendungszweck: SPRY2 Rabbit pAb

Sequenz: MEARAQSGNG SQPLLQTPRD GGRQRGEPDP RDALTQQVHV LSLDQIRAIR NTNEYTEGPT VVPRPGLKPA PRPSTQHKHE RLHGLPEHRQ PPRLQHSQVH

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SPRY2 (NP_005833.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SPRY2

Target: SPRY2 (Sprouty Homolog 2 (SPRY2))

Andere Bezeichnung: SPRY2

Hintergrund: This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.,SPRY2,IGAN3,hSPRY2,Signal Transduction,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Neuroscience,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Angiogenesis,SPRY2

Molekulargewicht: 34kDa

Gen-ID: 10253

UniProt: O43597

Pathways: EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation